Expression of Antiangiogenic Factors in the Placental Structures in Pre-Eclampsia
Comparative morphological study of the placentas was carried out in women with pregnancy aggravated by the development of pre-eclampsia. Immunohistochemical methods showed increased expression of endoglin (CD105) and VEGFR1 in all placental structures. The intensity of endoglin and VEGFR1 expression...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 2012-12, Vol.154 (2), p.287-291 |
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| container_title | Bulletin of experimental biology and medicine |
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| creator | Shchyogolev, A. I. Dubova, E. A. Pavlova, K. A. Lyapin, V. M. Sukhikh, G. T. |
| description | Comparative morphological study of the placentas was carried out in women with pregnancy aggravated by the development of pre-eclampsia. Immunohistochemical methods showed increased expression of endoglin (CD105) and VEGFR1 in all placental structures. The intensity of endoglin and VEGFR1 expression was maximum in the syncytiotrophoblast and extravillous cytotrophoblast cells in severe pre-eclampsia. |
| doi_str_mv | 10.1007/s10517-012-1932-0 |
| format | Article |
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| subjects | Adult Antigens, CD - metabolism Antimitotic agents Antineoplastic agents Biomedical and Life Sciences Biomedicine Cell Biology Endoglin Female Humans Internal Medicine Laboratory Medicine Pathology Placenta - metabolism Pre-Eclampsia - metabolism Preeclampsia Pregnancy Receptors, Cell Surface - metabolism Trophoblasts - metabolism Vascular endothelial growth factor Vascular Endothelial Growth Factor Receptor-1 - metabolism |
| title | Expression of Antiangiogenic Factors in the Placental Structures in Pre-Eclampsia |
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