Growth during Infancy and Childhood, and Adiposity at Age 16 Years: Ages 2 to 7 Years Are Pivotal

Objective To assess the period during infancy and childhood in which growth is most associated with adolescent adiposity and the metabolic syndrome (MS) and whether this differs depending on maternal smoking during pregnancy. Study design A longitudinal population-based cohort study among 772 girls...

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Veröffentlicht in:The Journal of pediatrics 2013-02, Vol.162 (2), p.287-292.e2
Hauptverfasser: Liem, Eryn T., MD, PhD, van Buuren, Stef, PhD, Sauer, Pieter J.J., MD, PhD, Jaspers, Merlijne, MSc, Stolk, Ronald P., MD, PhD, Reijneveld, Sijmen A., MD, PhD
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Sprache:eng
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Zusammenfassung:Objective To assess the period during infancy and childhood in which growth is most associated with adolescent adiposity and the metabolic syndrome (MS) and whether this differs depending on maternal smoking during pregnancy. Study design A longitudinal population-based cohort study among 772 girls and 708 boys. Results Weight gains between ages 2-4 years and ages 4-7 years were most strongly associated with higher body mass index (BMI), sum of skinfold measurements, body fat percentage, and waist circumference at age 16. A one SD increase in weight between ages 2-4 and 4-7 years was associated with increases in outcome measures of +0.82 to +1.47 SDs (all P  
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2012.07.053