Epinephrine (adrenaline) absorption from new-generation, taste-masked sublingual tablets: A preclinical study

[...]many patients at risk of anaphylaxis do not carry their epinephrine autoinjectors with them consistently because of bulky autoinjector size. [...]when anaphylaxis occurs, epinephrine autoinjectors are underused, even by patients who have life-threatening respiratory or cardiovascular symptoms.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of allergy and clinical immunology 2013-01, Vol.131 (1), p.236-238
Hauptverfasser:	Rachid, Ousama, BPharm, MSc, Rawas-Qalaji, Mutasem M., PhD, Simons, F. Estelle R., MD, Simons, Keith J., PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Sublingual Allergy and Immunology Animals Biological and medical sciences Cellulose Colleges & universities Drug Evaluation, Preclinical Epinephrine - administration & dosage Epinephrine - pharmacokinetics Female Fundamental and applied biological sciences. Psychology Fundamental immunology Human subjects Immunopathology Medical sciences Molecular weight Plasma Rabbits Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Tablets
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	[...]many patients at risk of anaphylaxis do not carry their epinephrine autoinjectors with them consistently because of bulky autoinjector size. [...]when anaphylaxis occurs, epinephrine autoinjectors are underused, even by patients who have life-threatening respiratory or cardiovascular symptoms.
ISSN:	0091-6749 1097-6825
DOI:	10.1016/j.jaci.2012.10.016