Polymorphism 677C→T MTHFR Gene in Mexican Mothers of Children With Complex Congenital Heart Disease

Congenital heart defects (CHD) are the third leading cause of death in children 0.05). Association was found between the maternal genotype (677/TT MTHFR) with the presence of complex CHD in their offspring. No differences in FA supplementation during any stage were found between groups.

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Bibliographische Detailangaben
Veröffentlicht in:	Pediatric cardiology 2013, Vol.34 (1), p.46-51
Hauptverfasser:	Balderrábano-Saucedo, Norma A., Sánchez-Urbina, Rocio, Sierra-Ramírez, José A., García-Hernández, Normand, Sánchez-Boiso, Adriana, Klunder-Klunder, Miguel, Arenas-Aranda, Diego, Bravo-Hernández, Gabriela, Noriega-Zapata, Penelope, Vizcaíno-Alarcón, Alfredo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Cardiac Surgery Cardiology Children's furniture Congenital heart disease Dietary Supplements Female Folic acid Folic Acid - genetics Folic Acid Deficiency - genetics Genes Genetic aspects Genetic polymorphisms Genetic Predisposition to Disease Heart Defects, Congenital - genetics Heart diseases Humans Infant Male Medicine Medicine & Public Health Methylenetetrahydrofolate Reductase (NADPH2) - genetics Mexico Mothers Original Article Polymorphism, Genetic Pregnancy Risk Factors Surveys and Questionnaires Vascular Surgery
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Beschreibung
Zusammenfassung:	Congenital heart defects (CHD) are the third leading cause of death in children 0.05). Association was found between the maternal genotype (677/TT MTHFR) with the presence of complex CHD in their offspring. No differences in FA supplementation during any stage were found between groups.
ISSN:	0172-0643 1432-1971
DOI:	10.1007/s00246-012-0380-y