Effect of Body Mass Index on Short- and Long-Term Outcomes After Transcatheter Aortic Valve Implantation

Better outcomes have been reported after percutaneous cardiac intervention in obese patients (“obesity paradox”). However, limited information is available on the effect of the body mass index on the outcomes after transcatheter aortic valve implantation (TAVI). We, therefore, sought to determine th...

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Veröffentlicht in:	The American journal of cardiology 2013-01, Vol.111 (2), p.231-236
Hauptverfasser:	van der Boon, Robert M.A., MSc, Chieffo, Alaide, MD, Dumonteil, Nicolas, MD, Tchetche, Didier, MD, Van Mieghem, Nicolas M., MD, Buchanan, Gill L., MBChB, Vahdat, Olivier, MD, Marcheix, Bertrand, MD, PhD, Serruys, Patrick W., MD, PhD, Fajadet, Jean, MD, Colombo, Antonio, MD, PhD, Carrié, Didier, MD, PhD, van Domburg, Ron T., PhD, de Jaegere, Peter P.T., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aortic Valve Aortic Valve Stenosis - complications Aortic Valve Stenosis - mortality Aortic Valve Stenosis - surgery Body Mass Index Cardiac Catheterization - methods Cardiovascular Cardiovascular disease Drug therapy Europe - epidemiology Follow-Up Studies Heart attacks Heart Valve Prosthesis Hospital Mortality - trends Humans Kaplan-Meier Estimate Length of Stay Mortality Obesity Obesity - complications Obesity - mortality Odds Ratio Postoperative Period Risk Assessment - methods Risk Factors Time Factors Treatment Outcome
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Zusammenfassung:	Better outcomes have been reported after percutaneous cardiac intervention in obese patients (“obesity paradox”). However, limited information is available on the effect of the body mass index on the outcomes after transcatheter aortic valve implantation (TAVI). We, therefore, sought to determine the effect of the body mass index on the short- and long-term outcomes in patients who underwent TAVI. The population consisted of 940 patients, of whom 25 (2.7%) were underweight, 384 had a (40.9%) normal weight, 372 (39.6%) were overweight, and 159 (16.9%) were obese. Overall, the obese patients were younger (79.7 ± 6.4 years vs 81.7 ± 7.3 and 80.8 ± 7.0 years, p = 0.008) and had a greater prevalence of preserved left ventricular and renal function. On univariate analysis, obese patients had a greater incidence of minor stroke (1.3% vs 0 and 0.3%, p = 0.03), minor vascular complications (15.7% vs 9.1% and 11.6%, p = 0.028) and acute kidney injury stage I (23.3% vs 10.7% and 16.1%, p
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2012.09.022