Medical Outcomes in African American Live Kidney Donors: A Matched Cohort Study

It is uncertain if live kidney donation increases future risk of hypertension and kidney disease in African Americans. We conducted a cohort study across two transplant centers enrolling African Americans who donated between 1993 and 2006. A comparison group of African American nondonors were select...

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Veröffentlicht in:	American journal of transplantation 2013-01, Vol.13 (1), p.111-118
Hauptverfasser:	Doshi, M. D., Goggins, M. O., Li, L., Garg, A. X.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult African American Arterial hypertension. Arterial hypotension Biological and medical sciences Black or African American Black People Blood and lymphatic vessels Cardiology. Vascular system Case-Control Studies Cohort Studies Female Glomerular Filtration Rate Humans hypertension kidney function Kidney Transplantation live kidney donors Male Medical sciences Miscellaneous Public health. Hygiene Public health. Hygiene-occupational medicine race Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue Donors Treatment Outcome
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Beschreibung
Zusammenfassung:	It is uncertain if live kidney donation increases future risk of hypertension and kidney disease in African Americans. We conducted a cohort study across two transplant centers enrolling African Americans who donated between 1993 and 2006. A comparison group of African American nondonors were selected from healthy participants in the Coronary Artery Risk Development in Young Adults (CARDIA) prospective cohort study. A total of 103 donors and 235 matched nondonors were assessed at mean ( ± SD) of 6.8 ± 2.3 and 6.4 ± 2.2 years after donation or cohort entry, respectively. The primary outcome was risk of hypertension in donors at follow‐up. The secondary outcomes were proportion of donors with eGFR
ISSN:	1600-6135 1600-6143 1600-6143
DOI:	10.1111/j.1600-6143.2012.04303.x