Stanniocalcin 1 is important for poststroke functionality, but dispensable for ischemic tolerance
Highlights ► STC1 lacking mice are sicker than littermates after ischemic stroke. ► Hypoxic preconditioning works despite the lack of STC1. ► STC1 deficiency leads to lower expression of IL-6 in ischemic brain. ► STC1 is not an important component of the blood-brain barrier.
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Veröffentlicht in: | Neuroscience 2013-01, Vol.229, p.49-54 |
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Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Highlights ► STC1 lacking mice are sicker than littermates after ischemic stroke. ► Hypoxic preconditioning works despite the lack of STC1. ► STC1 deficiency leads to lower expression of IL-6 in ischemic brain. ► STC1 is not an important component of the blood-brain barrier. |
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ISSN: | 0306-4522 1873-7544 |
DOI: | 10.1016/j.neuroscience.2012.10.062 |