The use of propolis as vaccine's adjuvant

Highlights ► Adjuvants are necessary for vaccine formulation. ► New adjuvants are required to overcome the available one's disadvantages. ► Propolis is a safe immunostimulator natural product. ► Several preparations of propolis are proven to be potent adjuvants. ► Encapsulated propolis flavonoi...

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Veröffentlicht in:	Vaccine 2012-12, Vol.31 (1), p.31-39
Hauptverfasser:	Ashry, El Sayed H. El, Ahmad, Tarek A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants Adjuvants, Immunologic - chemistry adverse effects Allergy and Immunology Aluminum Alzheimer's disease Applied microbiology Biological and medical sciences Cytokines Flavonoids Fundamental and applied biological sciences. Psychology Humans immune response Immune system Immunopotentiators languages Medical research Microbiology Natural products Propolis Propolis - chemistry Propolis - immunology Studies Toxicity Vaccines Vaccines - immunology Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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Beschreibung
Zusammenfassung:	Highlights ► Adjuvants are necessary for vaccine formulation. ► New adjuvants are required to overcome the available one's disadvantages. ► Propolis is a safe immunostimulator natural product. ► Several preparations of propolis are proven to be potent adjuvants. ► Encapsulated propolis flavonoids mixture is the most promising formulation.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2012.10.095