Autoimmune disorders after immunisation with Influenza A/H1N1 vaccines with and without adjuvant: EudraVigilance data and literature review

Highlights ► Reports of AID received in EudraVigilance for pandemic vaccines were analysed. ► GBS was the AID with the highest number of reports. ► No difference seen in AID reporting between adjuvanted and unadjuvanted vaccines. ► Literature review does not suggest any difference either.

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Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2012-11, Vol.30 (49), p.7123-7129
Hauptverfasser:	Isai, Alina, Durand, Julie, Le Meur, Steven, Hidalgo-Simon, Ana, Kurz, Xavier
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants Adjuvants, Immunologic - administration & dosage Adjuvants, Immunologic - adverse effects adverse effects Allergy and Immunology Antigens Autoimmune diseases Autoimmune Diseases - chemically induced Autoimmune Diseases - epidemiology Autoimmune disorders Avian flu Encephalitis Encephalomyelitis, Acute Disseminated - chemically induced Encephalomyelitis, Acute Disseminated - epidemiology EudraVigilance Guillain-Barre Syndrome Guillain-Barre Syndrome - chemically induced Guillain-Barre Syndrome - epidemiology H1N1 vaccines Humans Immunization influenza Influenza A Virus, H1N1 Subtype - immunology Influenza Vaccines - administration & dosage Influenza Vaccines - adverse effects Influenza, Human - prevention & control insulin-dependent diabetes mellitus Literature reviews Multiple sclerosis pandemic Pandemics Population Production capacity Purpura, Thrombocytopenic, Idiopathic - chemically induced Purpura, Thrombocytopenic, Idiopathic - epidemiology sclerosis Surveillance Swine flu thrombocytopenic purpura vaccination Vaccines World Health Organization
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Beschreibung
Zusammenfassung:	Highlights ► Reports of AID received in EudraVigilance for pandemic vaccines were analysed. ► GBS was the AID with the highest number of reports. ► No difference seen in AID reporting between adjuvanted and unadjuvanted vaccines. ► Literature review does not suggest any difference either.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2012.09.032