First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers

First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers

A series of molecularly imprinted polymers (MIPs) were prepared in the presence of a synthetic galactoside locked in a (1,4)B boat conformation. This study demonstrates that, depending on the polymerisation technique, an organic material can selectively bind a carbohydrate in a biologically relevant...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2012-11, Vol.48 (86), p.10684-10686
Hauptverfasser: de Talancé, Vincent Lemau, Massinon, Olivier, Baati, Rachid, Wagner, Alain, Vincent, Stéphane P
Format: Artikel
Sprache:eng
Schlagworte:
Biomimetic Materials - chemistry
Boats
Carbohydrates
Discrimination
Galactosides
Galactosides - chemistry
Imprinted polymers
Lectins
Lectins - chemistry
Molecular Conformation
Molecular Imprinting
Organic materials
Polyenes - chemistry
Polymerization
Polymers - chemistry
Solvents - chemistry
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Beschreibung
Zusammenfassung:A series of molecularly imprinted polymers (MIPs) were prepared in the presence of a synthetic galactoside locked in a (1,4)B boat conformation. This study demonstrates that, depending on the polymerisation technique, an organic material can selectively bind a carbohydrate in a biologically relevant boat conformation.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc35386e