Mitral valve repair or replacement for ischemic mitral regurgitation? The Italian Study on the Treatment of Ischemic Mitral Regurgitation (ISTIMIR)

Objective It is uncertain whether mitral valve replacement is really inferior to mitral valve repair for the treatment of chronic ischemic mitral regurgitation. This multicenter study aimed at providing a contribution to this issue. Methods Of 1006 patients with chronic ischemic mitral regurgitation...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2013, Vol.145 (1), p.128-139
Hauptverfasser:	Lorusso, Roberto, MD, PhD, Gelsomino, Sandro, MD, PhD, Vizzardi, Enrico, MD, D'Aloia, Antonio, MD, De Cicco, Giuseppe, MD, Lucà, Fabiana, MD, Parise, Orlando, MSc, Gensini, Gian Franco, MD, Stefàno, Pierluigi, MD, Livi, Ugolino, MD, Vendramin, Igor, MD, Pacini, Davide, MD, Di Bartolomeo, Roberto, MD, Miceli, Antonio, MD, PhD, Varone, Egidio, MD, Glauber, Mattia, MD, Parolari, Alessandro, MD, Giuseppe Arlati, Francesco, MD, Alamanni, Francesco, MD, Serraino, Filiberto, MD, Renzulli, Attilio, MD, Messina, Antonio, MD, PhD, Troise, Giovanni, MD, Mariscalco, Giovanni, MD, PhD, Cottini, Marzia, MD, Beghi, Cesare, MD, Nicolini, Francesco, MD, PhD, Gherli, Tiziano, MD, Borghetti, Valentino, MD, Pardini, Alessandro, MD, Caimmi, Philippe-Primo, MD, Micalizzi, Ezio, MD, Fino, Carlo, MD, Ferrazzi, Paolo, MD, Di Mauro, Michele, MD, Calafiore, Antonio Maria, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cardiothoracic Surgery Chronic Disease Female Heart Valve Prosthesis Heart Valve Prosthesis Implantation - adverse effects Heart Valve Prosthesis Implantation - instrumentation Heart Valve Prosthesis Implantation - mortality Humans Italy Kaplan-Meier Estimate Logistic Models Male Middle Aged Mitral Valve Annuloplasty - adverse effects Mitral Valve Annuloplasty - mortality Mitral Valve Insufficiency - etiology Mitral Valve Insufficiency - mortality Mitral Valve Insufficiency - physiopathology Mitral Valve Insufficiency - surgery Multivariate Analysis Myocardial Ischemia - complications Myocardial Ischemia - mortality Myocardial Ischemia - physiopathology Postoperative Complications - etiology Postoperative Complications - surgery Propensity Score Proportional Hazards Models Prosthesis Design Reoperation Retrospective Studies Risk Assessment Risk Factors Stroke Volume Time Factors Treatment Outcome Ventricular Function, Left
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Zusammenfassung:	Objective It is uncertain whether mitral valve replacement is really inferior to mitral valve repair for the treatment of chronic ischemic mitral regurgitation. This multicenter study aimed at providing a contribution to this issue. Methods Of 1006 patients with chronic ischemic mitral regurgitation and impaired left ventricular function (ejection fraction
ISSN:	0022-5223 1097-685X
DOI:	10.1016/j.jtcvs.2012.09.042