Expression and modulation of adipolin/C1qdc2: a novel adipokine in human and murine ATDC-5 chondrocyte cell line
Here we describe, for the first time, adipolin expression in human chondrocytes as well as the intracellular mechanism involved in its regulation. [...]we show that adipolin expression is modulated by pro- and anti-inflammatory factors in chondrocytes.
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Veröffentlicht in: | Annals of the rheumatic diseases 2013-01, Vol.72 (1), p.140-142 |
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container_title | Annals of the rheumatic diseases |
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creator | Conde, Javier Scotece, Morena López, Verónica Gómez, Rodolfo Lago, Francisca Pino, Jesús Gómez-Reino, Juan Jesús Gualillo, Oreste |
description | Here we describe, for the first time, adipolin expression in human chondrocytes as well as the intracellular mechanism involved in its regulation. [...]we show that adipolin expression is modulated by pro- and anti-inflammatory factors in chondrocytes. |
doi_str_mv | 10.1136/annrheumdis-2012-201693 |
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subjects | Adipokines - genetics Adipokines - metabolism Animals Biological and medical sciences Cell Differentiation - physiology Cell Line Chondrocytes - cytology Chondrocytes - metabolism Diseases of the osteoarticular system Gene expression Gene Expression Regulation Humans Medical sciences Mice Obesity Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Rodents |
title | Expression and modulation of adipolin/C1qdc2: a novel adipokine in human and murine ATDC-5 chondrocyte cell line |
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