Comparison of global left ventricular function using 20 phases with 10-phase reconstructions in multidetector-row computed tomography

To compare the measurement of global left-ventricular (LV) function parameters of 64-slice multidetector-row computed tomography (MDCT) between 20- and 10-reconstruction phases. Fifty five patients with suspected or known coronary artery disease underwent 64-slice MDCT. LV end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) were measured from MDCT data sets using threshold-based volume segmentation and reconstruction at every 5% (20 phases) and 10% (10 phases) step through the R-R interval. These global functional parameters were compared to those obtained via two-dimensional transthoracic echocardiography (2D-TTE), considering the reference standard. The required time for CT data analysis was checked. Agreement for parameters of LV global function was determined using Pearson’s correlation coefficient ( r ) and Bland–Altman analysis. LV volumes (EDV −5% 87.5 ± 17.1 ml, EDV −10% 87.7 ± 16.3 ml; ESV −5% 32.4 ± 10.6 ml, ESV −10% 31.9 ± 9.9 ml; SV −5% 55.1 ± 10.5 ml, SV −10% 55.8 ± 9.9 ml; mean ± SD) and EF (EF −5% 63.4 ± 6.2%, EF −10% 63.9 ± 5.8%) did not differ significantly between the 20- and 10 phase reconstructions, and evidenced good to excellent correlation ( r = 0.786–0.896, all P