Extensive emphysematous pyelonephritis in a renal allograft treated conservatively: case report and review of the literature

Emphysematous pyelonephritis (EPN) is a rare occurrence in renal allografts. An aggressive approach resulting in transplant nephrectomy is viewed as the standard of care. Over the recent years, treatment with percutaneous drainage (PCD) of the renal and perinephric collections and appropriate antibi...

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Veröffentlicht in:Transplant infectious disease 2012-12, Vol.14 (6), p.E150-E155
Hauptverfasser: Alexander, S., Varughese, S., David, V.G., Kodgire, S.V., Mukha, R.P., Kekre, N.S., Tamilarasi, V., Jacob, C.K., John, G.T.
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container_end_page E155
container_issue 6
container_start_page E150
container_title Transplant infectious disease
container_volume 14
creator Alexander, S.
Varughese, S.
David, V.G.
Kodgire, S.V.
Mukha, R.P.
Kekre, N.S.
Tamilarasi, V.
Jacob, C.K.
John, G.T.
description Emphysematous pyelonephritis (EPN) is a rare occurrence in renal allografts. An aggressive approach resulting in transplant nephrectomy is viewed as the standard of care. Over the recent years, treatment with percutaneous drainage (PCD) of the renal and perinephric collections and appropriate antibiotics has been reported with good success in lesser grades of this infection. Only 4 cases of extensive EPN disease with Escherichia coli, treated with conservative management, are reported in the English‐language literature. We present a case of severe EPN caused by Klebsiella pneumoniae, successfully managed with early PCD, and propose a step‐up strategy aimed toward graft preservation.
doi_str_mv 10.1111/tid.12016
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subjects Anti-Bacterial Agents - therapeutic use
Bacteriology
Drainage
Drug Resistance, Multiple, Bacterial
emphysematous pyelonephritis
Female
Humans
Immunocompromised Host
Kidney Transplantation - adverse effects
Klebsiella Infections - drug therapy
Klebsiella Infections - etiology
Klebsiella pneumoniae - drug effects
Klebsiella pneumoniae - isolation & purification
Klebsiella species
Middle Aged
percutaneous drainage
Pyelonephritis - drug therapy
Pyelonephritis - etiology
Pyelonephritis - surgery
renal allograft
step‐up strategy
title Extensive emphysematous pyelonephritis in a renal allograft treated conservatively: case report and review of the literature
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