Extensive emphysematous pyelonephritis in a renal allograft treated conservatively: case report and review of the literature

Emphysematous pyelonephritis (EPN) is a rare occurrence in renal allografts. An aggressive approach resulting in transplant nephrectomy is viewed as the standard of care. Over the recent years, treatment with percutaneous drainage (PCD) of the renal and perinephric collections and appropriate antibi...

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Veröffentlicht in:Transplant infectious disease 2012-12, Vol.14 (6), p.E150-E155
Hauptverfasser: Alexander, S., Varughese, S., David, V.G., Kodgire, S.V., Mukha, R.P., Kekre, N.S., Tamilarasi, V., Jacob, C.K., John, G.T.
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Sprache:eng
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Zusammenfassung:Emphysematous pyelonephritis (EPN) is a rare occurrence in renal allografts. An aggressive approach resulting in transplant nephrectomy is viewed as the standard of care. Over the recent years, treatment with percutaneous drainage (PCD) of the renal and perinephric collections and appropriate antibiotics has been reported with good success in lesser grades of this infection. Only 4 cases of extensive EPN disease with Escherichia coli, treated with conservative management, are reported in the English‐language literature. We present a case of severe EPN caused by Klebsiella pneumoniae, successfully managed with early PCD, and propose a step‐up strategy aimed toward graft preservation.
ISSN:1398-2273
1399-3062
DOI:10.1111/tid.12016