Cytisin amidophosphate--the new cytoprotector

This article describes the results of a clinical study of O,O dimethyl-N-cytinizylphosphate in healthy volunteers and 142 patients with the verified diagnosis of acute toxic hepatitis. The tolerability was good. The efficiency of the drug is considered to be very high, normalization of the state too...

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Veröffentlicht in:	Hiroshima journal of medical sciences 2012-09, Vol.61 (3), p.45-49
Hauptverfasser:	Zhumadilov, Zhaxybay, Nurgozhin, Talgat, Gulyaev, Alexandr, Zhaugasheva, Sabira, Gazaliyev, Arystan, Ermekbayeva, Bakytgul, Abuova, Gulnara, Kenessary, Almas
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Adult Alkaloids - administration & dosage Alkaloids - chemistry Antioxidants - administration & dosage Antioxidants - chemistry Chemical and Drug Induced Liver Injury - drug therapy Cytoprotection - drug effects Female Humans Male Middle Aged Organophosphorus Compounds - administration & dosage Organophosphorus Compounds - chemistry Oxidative Stress - drug effects Treatment Outcome Young Adult
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Zusammenfassung:	This article describes the results of a clinical study of O,O dimethyl-N-cytinizylphosphate in healthy volunteers and 142 patients with the verified diagnosis of acute toxic hepatitis. The tolerability was good. The efficiency of the drug is considered to be very high, normalization of the state took less time in comparison with standard treatment; a significant improvement was achieved immediately after the first injection.
ISSN:	0018-2052