Response: The Diversity of Proteins Linking Xist to Gene Silencing

Response: The Diversity of Proteins Linking Xist to Gene Silencing

In this issue, Nechanitzky et al. question the role of SATB proteins in conferring cellular competence to respond to Xist. Here, Wutz and Agrelo respond, discussing ways to reconcile the available data. Both groups agree that multiple redundant factors may contribute in parallel.

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Bibliographische Detailangaben
Veröffentlicht in:Developmental cell 2012-10, Vol.23 (4), p.680-680
Hauptverfasser: Wutz, Anton, Agrelo, Ruben
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Female
Matrix Attachment Region Binding Proteins - deficiency
Transcription Factors - deficiency
X Chromosome Inactivation
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Zusammenfassung:In this issue, Nechanitzky et al. question the role of SATB proteins in conferring cellular competence to respond to Xist. Here, Wutz and Agrelo respond, discussing ways to reconcile the available data. Both groups agree that multiple redundant factors may contribute in parallel.
ISSN:1534-5807
1878-1551
DOI:10.1016/j.devcel.2012.09.017