Plasma adiponectin before and after kidney transplantation
Summary The role of plasma adiponectin (ADPN) in patients with impaired kidney function and following kidney transplantation (Tx) is debated. We aimed to: (i) determine whether pretransplant ADPN level is an independent risk factor for deterioration of glucose tolerance including development of new‐...
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Veröffentlicht in: | Transplant international 2012-11, Vol.25 (11), p.1194-1203 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Summary
The role of plasma adiponectin (ADPN) in patients with impaired kidney function and following kidney transplantation (Tx) is debated. We aimed to: (i) determine whether pretransplant ADPN level is an independent risk factor for deterioration of glucose tolerance including development of new‐onset diabetes mellitus after Tx, (ii) describe which parameters that influence the ADPN concentration before and after Tx. Fifty‐seven nondiabetic kidney allograft recipients and 40 nondiabetic uraemic patients were included. The Tx group was examined at baseline and 3 and 12 months after Tx. The uraemic control group was examined twice, separated by 12 months. ADPN levels declined significantly following Tx (P |
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ISSN: | 0934-0874 1432-2277 |
DOI: | 10.1111/j.1432-2277.2012.01560.x |