Quinalphos induced oxidative stress and histoarcheitectural alterations in adult male albino rats

Quinalphos induced oxidative stress and histoarcheitectural alterations in adult male albino rats

Graphical abstract Highlights ► Quinalphos exposure induces oxidative stress in dose & time dependent manner. ► Sub-lethal doses of quinalphos cause hepatic injury. ► Quinalphos toxicity may be due to compromised antioxidant potential.

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Veröffentlicht in:Environmental toxicology and pharmacology 2012-11, Vol.34 (3), p.673-678
Hauptverfasser: Subramaneyaan, Mythily, Jain, Smita, Yadav, Chandrashekhar, Arora, Vinod K, Banerjee, Basu D, Ahmed, Rafat S
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antioxidants
Emergency
FRAP
Glutathione - metabolism
Glutathione Transferase - metabolism
Insecticides - toxicity
Lipid Peroxidation - drug effects
Liver - drug effects
Liver - metabolism
Liver - pathology
Male
Malondialdehyde - metabolism
Organothiophosphorus Compounds - toxicity
Oxidative Stress
Pesticides
Quinalphos
Rats
Rats, Wistar
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Beschreibung
Zusammenfassung:Graphical abstract Highlights ► Quinalphos exposure induces oxidative stress in dose & time dependent manner. ► Sub-lethal doses of quinalphos cause hepatic injury. ► Quinalphos toxicity may be due to compromised antioxidant potential.
ISSN:1382-6689
1872-7077
DOI:10.1016/j.etap.2012.10.003