Contractile Reserve Assessed by Three-Dimensional Global Circumferential Strain as a Predictor of Cardiovascular Events in Patients with Idiopathic Dilated Cardiomyopathy

Background It has been suggested that the assessment of left ventricular contractile reserve during dobutamine infusion can improve prognostic evaluation for patients with idiopathic dilated cardiomyopathy (DCM). However, the assessment of contractile reserve is often subjective, while three-dimensi...

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Veröffentlicht in:	Journal of the American Society of Echocardiography 2012-12, Vol.25 (12), p.1299-1308
Hauptverfasser:	Matsumoto, Kensuke, MD, Tanaka, Hidekazu, MD, PhD, Kaneko, Akihiro, MD, Ryo, Keiko, MD, PhD, Fukuda, Yuko, MD, Tatsumi, Kazuhiro, MD, PhD, Kawai, Hiroya, MD, PhD, Hirata, Ken-ichi, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cardiomyopathy, Dilated - complications Cardiomyopathy, Dilated - diagnostic imaging Cardiovascular Contractile reserve Dilated cardiomyopathy Dobutamine Echocardiography Echocardiography - methods Echocardiography, Three-Dimensional - methods Elasticity Imaging Techniques - methods Female Heart failure Humans Male Middle Aged Reproducibility of Results Sensitivity and Specificity Three-dimensional speckle-tracking strain Vasodilator Agents Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - etiology
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Zusammenfassung:	Background It has been suggested that the assessment of left ventricular contractile reserve during dobutamine infusion can improve prognostic evaluation for patients with idiopathic dilated cardiomyopathy (DCM). However, the assessment of contractile reserve is often subjective, while three-dimensional (3D) speckle-tracking can quantify three different components of strain simultaneously from all 16 left ventricular segments. The purpose of this study was to investigate the capability of multidirectional deformational indices assessed by 3D speckle-tracking strain to predict cardiac events in patients with DCM. Whether such assessment under dobutamine infusion can enhance this method’s predictive capability was also evaluated by comparison with two-dimensional (2D) speckle-tracking. Methods Sixty-five patients with DCM with a mean ejection fraction of 34 ± 8% (all
ISSN:	0894-7317 1097-6795
DOI:	10.1016/j.echo.2012.09.018