Catalytic Asymmetric Synthesis of Substituted Morpholines and Piperazines
Under two conditions: Hydroamination catalyzed by group 4 metals is featured in the modular and enantioselective synthesis of 3‐substituted morpholines and the diastereoselective synthesis of 2,5‐substituted piperazines.
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| Veröffentlicht in: | Angewandte Chemie International Edition 2012-12, Vol.51 (49), p.12219-12223 |
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| container_end_page | 12223 |
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| container_issue | 49 |
| container_start_page | 12219 |
| container_title | Angewandte Chemie International Edition |
| container_volume | 51 |
| creator | Zhai, Huimin Borzenko, Andrey Lau, Ying Yin Ahn, Shin Hye Schafer, Laurel L. |
| description | Under two conditions: Hydroamination catalyzed by group 4 metals is featured in the modular and enantioselective synthesis of 3‐substituted morpholines and the diastereoselective synthesis of 2,5‐substituted piperazines. |
| doi_str_mv | 10.1002/anie.201206826 |
| format | Article |
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| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | asymmetric catalysis heterocycles hydroamination titanium zirconium |
| title | Catalytic Asymmetric Synthesis of Substituted Morpholines and Piperazines |
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