Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with systemic lupus erythematosus and good outcome with rituximab treatment

A patient with chronic inflammatory demyelinating polyradiculoneuropathy and systemic lupus erythematosus arising after rubella vaccination was initially treated with plasmapheresis, corticosteroids and intravenous immunoglobulins, with partial response. After shift to rituximab, most clinical sympt...

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Veröffentlicht in:	Rheumatology international 2012-12, Vol.32 (12), p.4061-4063
Hauptverfasser:	Sanz, P. G., García Méndez, C. V., Cueto, A. L., Silva, V. B., Walther, J. C., Diez, R. A., Martins, S., Giannaula, R. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - therapeutic use Adult Antibodies, Monoclonal, Murine-Derived - therapeutic use Antirheumatic Agents - therapeutic use Female Humans Immunoglobulins, Intravenous - therapeutic use Lupus Erythematosus, Systemic - complications Lupus Erythematosus, Systemic - drug therapy Medicine Medicine & Public Health Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - complications Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - drug therapy Retreatment Rheumatology Rituximab Short Communication Treatment Outcome
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Zusammenfassung:	A patient with chronic inflammatory demyelinating polyradiculoneuropathy and systemic lupus erythematosus arising after rubella vaccination was initially treated with plasmapheresis, corticosteroids and intravenous immunoglobulins, with partial response. After shift to rituximab, most clinical symptoms improved markedly, emphasizing the possible role of this monoclonal antibody in conventional therapy-resistant cases.
ISSN:	0172-8172 1437-160X
DOI:	10.1007/s00296-011-2130-5