Intercellular K+ accumulation depolarizes Type I vestibular hair cells and their associated afferent nerve calyx
Graphical abstract Highlights ► K+ can accumulate in the synaptic cleft around Type I hair cells. ► K+ accumulation depolarizes both the pre- and postsynaptic membranes. ► The depolarization produced by K+ accumulation participates in afferent vestibular signaling.
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| Veröffentlicht in: | Neuroscience 2012-12, Vol.227, p.232-246 |
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| container_title | Neuroscience |
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| creator | Contini, D Zampini, V Tavazzani, E Magistretti, J Russo, G Prigioni, I Masetto, S |
| description | Graphical abstract Highlights ► K+ can accumulate in the synaptic cleft around Type I hair cells. ► K+ accumulation depolarizes both the pre- and postsynaptic membranes. ► The depolarization produced by K+ accumulation participates in afferent vestibular signaling. |
| doi_str_mv | 10.1016/j.neuroscience.2012.09.051 |
| format | Article |
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| subjects | Action Potentials - physiology Afferent Pathways - physiology Animals Biological and medical sciences Biophysical Phenomena - physiology Biophysics Ear and associated structures. Auditory pathways and centers. Hearing. Vocal organ. Phonation. Sound production. Echolocation Electric Stimulation Fundamental and applied biological sciences. Psychology hair cell Hair Cells, Vestibular - classification Hair Cells, Vestibular - metabolism In Vitro Techniques Intracellular Fluid - metabolism Mice Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration nerve afferent calyx Nerve Net - physiology Neurology Patch-Clamp Techniques Potassium - metabolism semicircular canal Vertebrates: nervous system and sense organs vestibular Vestibule, Labyrinth - cytology |
| title | Intercellular K+ accumulation depolarizes Type I vestibular hair cells and their associated afferent nerve calyx |
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