A concomitant case of giant cell arteritis and microscopic polyangiitis with hemoperitoneum by rupture of the gastroepiploic artery

Giant cell arteritis (GCA) mainly involves large-sized arteries, while microscopic polyangiitis (mPA), characterized by pauci-immune necrotizing vasculitis, mainly affects small-sized vessels. We report a very rare concomitant case of GCA diagnosed by temporal artery biopsy and mPA with a high titer...

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Veröffentlicht in:Modern rheumatology 2012-11, Vol.22 (6), p.934-938
Hauptverfasser: Fujii, Kenji, Tsutsumi, Tomomi, Takaoka, Kensuke, Osugi, Yasuhiro, Ando, Satoshi, Koyama, Yoshinobu
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Sprache:eng
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Zusammenfassung:Giant cell arteritis (GCA) mainly involves large-sized arteries, while microscopic polyangiitis (mPA), characterized by pauci-immune necrotizing vasculitis, mainly affects small-sized vessels. We report a very rare concomitant case of GCA diagnosed by temporal artery biopsy and mPA with a high titer of myeloperoxidase antineutrophil cytoplasmic antibody, exacerbation of interstitial pneumonia, and suspected rapidly progressive glomerulonephritis. The patient died by sudden rupture of the gastroepiploic artery (medium-sized vessel), which may have been triggered by GCA and/or mPA.
ISSN:1439-7595
1439-7609
DOI:10.1007/s10165-012-0610-4