functional effect of soybean extract and isolated isoflavone on myocardial infarction and ventricular dysfunction: The soybean extract on myocardial infarction

BACKGROUND: Myocardial infarction is a public health problem. Functional food is an alternative treatment for cardiovascular diseases. OBJECTIVE: The objective was to analyze the functional and anatomopathological post-myocardial-infarction effects of soybean extract (SE) and isoflavone (IF). METHOD...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2012-12, Vol.23 (12), p.1740-1748
Hauptverfasser:	Miguez, Ana C, Francisco, Julio C, Barberato, Sílvio H, Simeoni, Rossana, Précoma, Dalton, do Amaral, Vivian Ferreira, Rodrigues, Edson, Olandoski, Márcia, de Noronha, Lúcia, Greca, Fernando H, de Carvalho, Katherine Athayde Teixeira, Faria-Neto, José Rocha, Guarita-Souza, Luiz C
Format:	Artikel
Sprache:	eng
Schlagworte:	adults Animals arginase Biological and medical sciences biomarkers Body Weight collagen Collagen - metabolism Eating - drug effects Echocardiography Feeding. Feeding behavior functional foods Fundamental and applied biological sciences. Psychology Glycine max - chemistry heart rate infarction Isoflavones - pharmacology L-Lactate Dehydrogenase - metabolism lactate dehydrogenase malate dehydrogenase myocardial infarction Myocardial Infarction - drug therapy Myocardial Infarction - pathology Myocardial Infarction - physiopathology Plant Extracts - chemistry Plant Extracts - pharmacology protective effect public health Rats Rats, Wistar soybeans Ventricular Dysfunction Ventricular Function, Left - drug effects Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Zusammenfassung:	BACKGROUND: Myocardial infarction is a public health problem. Functional food is an alternative treatment for cardiovascular diseases. OBJECTIVE: The objective was to analyze the functional and anatomopathological post-myocardial-infarction effects of soybean extract (SE) and isoflavone (IF). METHODS: Myocardial infarction was induced in adult Wistar rats. After 5 days, an echocardiogram was performed to determine heart rate (HR), ejection fraction (EF), systolic volume (LVESV) and diastolic volume (LVEDV). Animals with ventricular dysfunction (EF
ISSN:	0955-2863 1873-4847
DOI:	10.1016/j.jnutbio.2011.05.017