Hypodense regions in unenhanced CT identify nonviable myocardium: validation versus 18F-FDG PET

Purpose The aim of the present study was to evaluate the accuracy of hypodense regions in non-contrast-enhanced cardiac computed tomography (unenhanced CT) to identify nonviable myocardial scar tissue. Methods Hypodense areas were visually identified in unenhanced CT of 80 patients in the left ventr...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2012-12, Vol.39 (12), p.1920-1926
Hauptverfasser:	Fuchs, Tobias A., Ghadri, Jelena R., Stehli, Julia, Gebhard, Catherine, Kazakauskaite, Egle, Klaeser, Bernd, Gaemperli, Oliver, Fiechter, Michael, Kaufmann, Philipp A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cardiology Cicatrix - diagnostic imaging Coronary Artery Disease - diagnostic imaging Female Fluorodeoxyglucose F18 Heart - diagnostic imaging Humans Imaging Male Medicine Medicine & Public Health Middle Aged Myocardium - pathology Nuclear Medicine Oncology Original Article Orthopedics Positron-Emission Tomography Radiology Radiopharmaceuticals Tomography, Emission-Computed, Single-Photon
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Zusammenfassung:	Purpose The aim of the present study was to evaluate the accuracy of hypodense regions in non-contrast-enhanced cardiac computed tomography (unenhanced CT) to identify nonviable myocardial scar tissue. Methods Hypodense areas were visually identified in unenhanced CT of 80 patients in the left ventricular anterior, apical, septal, lateral and inferior myocardium and CT density was measured in Hounsfield units (HU). Findings were compared to 18 F-fluorodeoxyglucose uptake by positron emission tomography (FDG PET), which served as the standard of reference to distinguish scar (
ISSN:	1619-7070 1619-7089
DOI:	10.1007/s00259-012-2212-y