In-vitro comparison of free oscillation rheometry (ReoRox) and rotational thromboelastometry (ROTEM) in trauma patients upon hospital admission

Plasma-based assays do not provide accurate information on haemostatic resuscitation hence viscoelastic point-of-care haemostatic assays such as rotational thromboelastometry (ROTEM Delta, Pentapharm) are used to monitor coagulopathy in trauma patients. Free oscillation rheometry (FOR) is a new whol...

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Veröffentlicht in:Blood coagulation & fibrinolysis 2012-12, Vol.23 (8), p.688-692
Hauptverfasser: Sølbeck, Sacha, Windeløv, Nis A, Bæk, Nicolai H, Nielsen, Jørn D, Ostrowski, Sisse R, Johansson, Pär I
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Sprache:eng
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Zusammenfassung:Plasma-based assays do not provide accurate information on haemostatic resuscitation hence viscoelastic point-of-care haemostatic assays such as rotational thromboelastometry (ROTEM Delta, Pentapharm) are used to monitor coagulopathy in trauma patients. Free oscillation rheometry (FOR) is a new whole blood haemostatic assay that measures not only the clot-forming process but also the initial viscous phase; this could potentially be of value when assessing traumatic coagulopathy. A comparative analysis between FOR and ROTEM was therefore performed. This is a prospective observational study of 40 adult trauma patients admitted to a level 1 trauma centre. Citrated whole blood was analysed with ROTEM EXTEM and FIBTEM assays and FOR Fibscreen1 and Fibscreen2 assays. Predefined variables of ROTEM and FOR were compared using Spearmanʼs ρ. ROTEM maximum clot function (MCF) in both EXTEM and FIBTEM correlated (P 
ISSN:0957-5235
1473-5733
DOI:10.1097/MBC.0b013e328351ebd6