Proteasome inhibition leads to dephosphorylation and downregulation of protein expression of members of the Akt/mTOR pathway in MCL

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Veröffentlicht in:	Leukemia 2012-11, Vol.26 (11), p.2442-2444
Hauptverfasser:	Hutter, G, Zimmermann, Y, Rieken, M, Hartmann, E, Rosenwald, A, Hiddemann, W, Dreyling, M
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/200 631/80/474/2085 631/80/86 692/699/67/1990/291/1621 AKT protein Biological and medical sciences Bortezomib Cancer Research Cell cycle Cell growth Critical Care Medicine Dephosphorylation Down-Regulation Drug therapy Gene expression Genes Genetic aspects Health aspects Hematologic and hematopoietic diseases Hematology Humans Intensive Internal Medicine Kinases letter-to-the-editor Letters to the editor Leukemia Lymphoma Lymphoma, Mantle-Cell - enzymology Lymphoma, Mantle-Cell - metabolism Lymphoma, Mantle-Cell - pathology Medical sciences Medicine Medicine & Public Health Neoplasm Proteins - genetics Oncology Oxidative stress Phosphorylation Physiological aspects Proteasome Endopeptidase Complex - drug effects Proteasome Inhibitors - pharmacology Proteasomes Protein expression Protein kinases Proteins Proto-Oncogene Proteins c-akt - metabolism TOR protein TOR Serine-Threonine Kinases - metabolism
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