Febrile pancytopenia and hepatosplenomegaly as leading symptoms of visceral leishmaniasis

The authors present a case report of a patient with febrile pancytopenia, hepatosplenomegaly and weight loss as main symptoms of visceral leishmaniasis. Standard treatment regimen with amphothericin B led to relapse of the disease after several weeks. The definitive cure of the disease was achieved...

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Veröffentlicht in:	Vnitřní lékar̆stvĭ 2012-10, Vol.58 (10), p.761-764
Hauptverfasser:	Polák, P, Svoboda, R, Kubáčková, P, Brychtová, Y, Panovská, A, Nohýnková, E, Husa, P, Freibergerová, M, Pařízková, R, Snelerová, M, Pýchová, M, Kamelander, J
Format:	Artikel
Sprache:	cze
Schlagworte:	Adult Fever - complications Hepatomegaly - complications Humans Leishmaniasis, Visceral - complications Leishmaniasis, Visceral - diagnosis Leishmaniasis, Visceral - drug therapy Male Pancytopenia - complications Splenomegaly - complications
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Zusammenfassung:	The authors present a case report of a patient with febrile pancytopenia, hepatosplenomegaly and weight loss as main symptoms of visceral leishmaniasis. Standard treatment regimen with amphothericin B led to relapse of the disease after several weeks. The definitive cure of the disease was achieved with cytostatic miltefosin (Impavido©), which is not registered in the Czech Republic. The aim of this article is to point out this imported protozoan infection and its basic clinical and laboratory features.
ISSN:	0042-773X