Analysis of native structures of soft materials by cryo scanning probe tomography

We propose a universal tool for structural analysis of soft/frozen-hydrated materials at a macromolecular level over a wide range of temperatures (-120 to +50 degree C). The cryogenic scanning probe microscope presented here allows detailed investigation and serial-section 3D tomography of soft matt...

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Veröffentlicht in:Soft matter 2012-01, Vol.8 (38), p.9756-9760
Hauptverfasser: Efimov, Anton E., Gnaegi, Helmut, Schaller, Raimund, Grogger, Werner, Hofer, Ferdinand, Matsko, Nadejda B.
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Sprache:eng
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Zusammenfassung:We propose a universal tool for structural analysis of soft/frozen-hydrated materials at a macromolecular level over a wide range of temperatures (-120 to +50 degree C). The cryogenic scanning probe microscope presented here allows detailed investigation and serial-section 3D tomography of soft matter under native-like conditions.
ISSN:1744-683X
1744-6848
DOI:10.1039/c2sm26050f