Persistence of anxiety disorders and concomitant changes in cortisol

Highlights ► We studied a clinical sample of 116 children and adolescents with anxiety disorders. ► We determined cortisol levels before and at 1 year follow-up after treatment of the anxiety disorder. ► Persistence of the disorder was associated with increased daytime cortisol production. ► Persist...

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Veröffentlicht in:	Journal of anxiety disorders 2012-08, Vol.26 (6), p.635-641
Hauptverfasser:	Dierckx, Bram, Dieleman, Gwen, Tulen, Joke H.M, Treffers, Philip D.A, Utens, Elisabeth M.W.J, Verhulst, Frank C, Tiemeier, Henning
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adolescents Adult and adolescent clinical studies Anxiety Anxiety disorders Anxiety Disorders - complications Anxiety Disorders - metabolism Anxiety Disorders - therapy Anxiety disorders. Neuroses Assessment Biological and medical sciences Child Child and adolescent psychiatry Child Behavior - physiology Children Circadian Rhythm Clinical Cortisol Female Follow-Up Studies Humans Hydrocortisone - metabolism Hypothalamo-Hypophyseal System - physiopathology Interpersonal Relations Longitudinal study Male Medical sciences Pituitary-Adrenal System - physiopathology Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Saliva - metabolism Stress, Psychological - complications Stress, Psychological - metabolism Stress, Psychological - therapy
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Beschreibung
Zusammenfassung:	Highlights ► We studied a clinical sample of 116 children and adolescents with anxiety disorders. ► We determined cortisol levels before and at 1 year follow-up after treatment of the anxiety disorder. ► Persistence of the disorder was associated with increased daytime cortisol production. ► Persistence was associated with a trend towards decreased morning rise as well. ► Results underscore importance of early and adequate treatment of anxiety disorders.
ISSN:	0887-6185 1873-7897
DOI:	10.1016/j.janxdis.2012.04.001