Contribution of the Complement System to Realization of Biological Fluid Cytotoxicity in Health and Disease

Contribution of the Complement System to Realization of Biological Fluid Cytotoxicity in Health and Disease

The cytotoxic effects of human blood serum were studied under normal and pathological conditions. The contribution of the complement system to the realization of this effect was demonstrated. Signifi cant differences in the serum capacity to kill foreign cells were detected for healthy subjects and...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2012-09, Vol.153 (5), p.658-660
Hauptverfasser: Arkhipova, E. N., Cherepov, A. B., Medvedeva, Yu. S., Alchinova, I. B., Karganov, M. Yu
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Asthma - immunology
Athletes
Biological products
Biomedical and Life Sciences
Biomedicine
Cattle
Cell Biology
Complement System Proteins - immunology
Complement System Proteins - metabolism
Complement System Proteins - pharmacology
Cytotoxins - immunology
Cytotoxins - metabolism
Cytotoxins - pharmacology
Furosemide
Heparin
Humans
Internal Medicine
Laboratory Medicine
Male
Pathology
Serum - immunology
Serum - metabolism
Sperm Motility - drug effects
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Zusammenfassung:The cytotoxic effects of human blood serum were studied under normal and pathological conditions. The contribution of the complement system to the realization of this effect was demonstrated. Signifi cant differences in the serum capacity to kill foreign cells were detected for healthy subjects and asthmatics. Bovine sperm suspension can serve as the test object for rapid evaluation of functional activity of the complement system.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-012-1791-8