Panton‐Valentine Leukocidin‐Producing Staphylococcal aureus: Report of Four Siblings

: Panton‐Valentine leukocidin (PVL)‐producing Staphylococcus aureus results in leukocyte destruction and tissue necrosis (Pediatric Dermatology 2007;24:401). It can be associated with a spectrum of clinical manifestations that range from localized staphylococcal skin infections to sometimes severe necrotizing pneumonia (Clin Infect Dis 1999;29:1128). We report a case of four siblings, three brothers whose atopic dermatitis was complicated by cutaneous lesions and furunculosis, while their 21‐month‐old sister had a fatal PVL positive staphylococcal pneumonia.