Quantifying acute changes in volume and nutritional status during haemodialysis using bioimpedance analysis

Aim: To determine the precision of multi‐frequency bioimpedance analysis (MFBIA) in quantifying acute changes in volume and nutritional status during haemodialysis, in patients with end‐stage renal disease (ESRD). Methods: Using whole‐body MFBIA, we prospectively studied changes in total body water (TBW), extracellular volume (ECV), intracellular volume (ICV), lean body mass (LBM), body cell mass (BCM) and fat mass (FM), pre‐ and post‐haemodialysis and tested the agreement of volume changes with corresponding acute weight change and ultrafiltration volume (UF) using Bland‐Altman analysis. Results: Forty‐four prevalent and 17 incident haemodialysis patients were studied (median age 55 years, 56% males). MFBIA‐derived TBW, ECV, ICV, LBM and BCM were significantly reduced after haemodialysis (P