Growth and Growth Hormone Treatment in Children with Chronic Diseases

Growth hormone has been available for treatment of various conditions for over 50 years. There have been a number of chronic disease states in which it has been used, such as chronic kidney disease, which became a US Food and Drug Administration (FDA)-approved indication in 1993. For other chronic d...

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Veröffentlicht in:	Endocrinology and metabolism clinics of North America 2012-12, Vol.41 (4), p.747-759
Hauptverfasser:	Pozzo, Alba Morales, MD, Kemp, Stephen F., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	beta-Thalassemia - complications Body Height - drug effects Burns Burns - complications Child Chronic Disease - drug therapy Chronic inflammation Chronic kidney disease Cystic fibrosis Cystic Fibrosis - drug therapy Endocrinology & Metabolism Familial Hypophosphatemic Rickets - complications Glucocorticoids - adverse effects Growth Disorders - drug therapy Growth Disorders - etiology Growth hormone Growth Hormone - therapeutic use Humans Inflammation - complications Recombinant Proteins - therapeutic use Renal Insufficiency, Chronic - complications Short bowel syndrome Short Bowel Syndrome - complications Short stature
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Beschreibung
Zusammenfassung:	Growth hormone has been available for treatment of various conditions for over 50 years. There have been a number of chronic disease states in which it has been used, such as chronic kidney disease, which became a US Food and Drug Administration (FDA)-approved indication in 1993. For other chronic disease states there have been clinical studies supporting its use, but they have not yet been approved as a indications by the FDA. Examples of such diseases are cystic fibrosis, chronic arthritis, short bowel syndrome, burn trauma, and hypophosphatemic rickets.
ISSN:	0889-8529 1558-4410
DOI:	10.1016/j.ecl.2012.07.001