Maintaining Poise: Commensal Microbiota Calibrate Interferon Responses
The mechanisms of how commensal bacteria impact systemic immunity are unclear. In this issue of Immunity, Abt et al. (2012) and Ganal et al. (2012) demonstrate that microbiota poise macrophages for induction of the type I interferon pathway after virus infection.
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| Veröffentlicht in: | Immunity (Cambridge, Mass.) Mass.), 2012-07, Vol.37 (1), p.10-12 |
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| container_title | Immunity (Cambridge, Mass.) |
| container_volume | 37 |
| creator | McAleer, Jeremy P. Kolls, Jay K. |
| description | The mechanisms of how commensal bacteria impact systemic immunity are unclear. In this issue of Immunity, Abt et al. (2012) and Ganal et al. (2012) demonstrate that microbiota poise macrophages for induction of the type I interferon pathway after virus infection. |
| doi_str_mv | 10.1016/j.immuni.2012.07.001 |
| format | Article |
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| identifier | ISSN: 1074-7613 |
| ispartof | Immunity (Cambridge, Mass.), 2012-07, Vol.37 (1), p.10-12 |
| issn | 1074-7613 1097-4180 |
| language | eng |
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| source | Cell Press Free Archives; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Antibiotics Bacteria Commensals Cytotoxicity DNA methylation Epigenetics Gene expression HIV Human immunodeficiency virus Immune system Immunity Infection Infections Interferon Macrophages Phosphorylation RNA polymerase Studies Transcription factors Viral infections |
| title | Maintaining Poise: Commensal Microbiota Calibrate Interferon Responses |
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