Different distribution patterns of lymphocytes and microglia in the hippocampus of patients with residual versus paranoid schizophrenia: Further evidence for disease course-related immune alterations?

Highlight ► Increased lymphocyte densities were identified in the hippocampus of patients with residual schizophrenia in contrast to increased microglia in paranoid schizophrenia.

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Bibliographische Detailangaben
Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2012-11, Vol.26 (8), p.1273-1279
Hauptverfasser:	Busse, Stefan, Busse, Mandy, Schiltz, Kolja, Bielau, Hendrik, Gos, Tomasz, Brisch, Ralf, Mawrin, Christian, Schmitt, Andrea, Jordan, Wolfgang, Müller, Ulf J, Bernstein, Hans-Gert, Bogerts, Bernhard, Steiner, Johann
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Antibodies Antigens, CD20 - metabolism Autopsy Blood-brain barrier Blood-Brain Barrier - immunology Blood-Brain Barrier - metabolism Brain CD20 CD20 antigen CD3 CD3 antigen Cell activation Cell migration Cerebrospinal fluid Cytokines Data processing Disease Progression Emotional behavior Hippocampus Hippocampus - cytology Hippocampus - immunology Hippocampus - metabolism Histocompatibility antigen HLA HLA-DR HLA-DR Antigens - immunology HLA-DR Antigens - metabolism Humans Inflammation Lymphocytes Lymphocytes - cytology Lymphocytes - immunology Lymphocytes - metabolism Lymphocytes B Lymphocytes T Mental disorders Microglia Microglia - cytology Microglia - immunology Microglia - metabolism Microglial cells Mononuclear phagocyte system Neuroimaging Peripheral blood Psychiatry Psychosis Schizophrenia Schizophrenia, Paranoid - immunology
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Beschreibung
Zusammenfassung:	Highlight ► Increased lymphocyte densities were identified in the hippocampus of patients with residual schizophrenia in contrast to increased microglia in paranoid schizophrenia.
ISSN:	0889-1591 1090-2139
DOI:	10.1016/j.bbi.2012.08.005