Cushing’s disease presenting with pituitary apoplexy

Abstract Pituitary tumour apoplexy is a rare but life threatening condition. Cushing’s disease usually presents with clinical features of Cushing’s syndrome. We report a 30-year-old male patient with Cushing’s disease who presented with severe headache and right third nerve palsy. MRI of the pituita...

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Veröffentlicht in:	Journal of clinical neuroscience 2012-11, Vol.19 (11), p.1586-1589
Hauptverfasser:	Chan, Daniel, Rong, Teo Cheng, Dalan, Rinkoo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Corticotroph adenoma Cushing’s disease Diabetes Insipidus - physiopathology Headache - etiology Humans Hypopituitarism - etiology Magnetic Resonance Imaging Male Neurologic Examination Neurology Neurosurgical Procedures Obesity, Abdominal - complications Oculomotor Nerve Diseases - complications Pituitary ACTH Hypersecretion - pathology Pituitary ACTH Hypersecretion - surgery Pituitary apoplexy Pituitary Apoplexy - pathology Pituitary Apoplexy - surgery Pituitary Gland - pathology Pituitary Hormones - blood Postoperative Complications - physiopathology Tomography, X-Ray Computed
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Zusammenfassung:	Abstract Pituitary tumour apoplexy is a rare but life threatening condition. Cushing’s disease usually presents with clinical features of Cushing’s syndrome. We report a 30-year-old male patient with Cushing’s disease who presented with severe headache and right third nerve palsy. MRI of the pituitary gland revealed a pituitary adenoma with infarction suggestive of apoplexy. After a transsphenoidal surgery he developed pan-hypopituitarism with diabetes insipidus. We also review the relevant literature.
ISSN:	0967-5868 1532-2653
DOI:	10.1016/j.jocn.2011.10.017