Differences of the association of anti-Müllerian hormone with clinical or biochemical characteristics between women with and without polycystic ovary syndrome

The aim of the present study was to compare the associations of anti-Müllerian hormone (AMH) with clinical or biochemical characteristics between women with and without polycystic ovary syndrome (PCOS). We also explored the optimal cutoff point of AMH to diagnose PCOS. A cross-sectional study was pe...

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Veröffentlicht in:Endocrine Journal 2012, Vol.59(9), pp.781-790
Hauptverfasser: Woo, Hee-Yeon, Kim, Kye-Hyun, Rhee, Eun-Jung, Park, Hyosoon, Lee, Mi-Kyung
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Sprache:eng
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Zusammenfassung:The aim of the present study was to compare the associations of anti-Müllerian hormone (AMH) with clinical or biochemical characteristics between women with and without polycystic ovary syndrome (PCOS). We also explored the optimal cutoff point of AMH to diagnose PCOS. A cross-sectional study was performed in 87 women diagnosed with PCOS and 53 healthy control subjects. Body mass index (BMI), indices of insulin resistance, metabolic syndrome-related variables, reproductive hormones and serum AMH were measured in all subjects. We conducted receiver operating characteristic (ROC) curve analysis to determine the cutoff of AMH for diagnosis of PCOS. Serum AMH levels were significantly (p
ISSN:0918-8959
1348-4540
DOI:10.1507/endocrj.EJ12-0055