Bisphenol A exposure modifies DNA methylation of imprint genes in mouse fetal germ cells

Bisphenol A (BPA) is an estrogenic environmental toxin widely used for the production of plastics. Human frequent exposure to this chemical has been proposed to be a potential public health risk. The objective of this study was to assess the effects of BPA on DNA methylation of imprinting genes in f...

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Veröffentlicht in:	Molecular biology reports 2012-09, Vol.39 (9), p.8621-8628
Hauptverfasser:	Zhang, Xi-Feng, Zhang, Lian-Jun, Feng, Yan-Ni, Chen, Bo, Feng, Yan-Min, Liang, Gui-Jin, Li, Lan, Shen, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Air Pollutants, Occupational - pharmacology Air Pollutants, Occupational - toxicity Animal Anatomy Animal Biochemistry Animals Benzhydryl Compounds Biomedical and Life Sciences CpG Islands DNA methylation DNA Methylation - drug effects Environmental Exposure Female Fetus - drug effects Gene Expression Regulation, Developmental - drug effects Genes Genomic Imprinting - drug effects Germ Cells - drug effects Germ Cells - metabolism Germination Histology Kruppel-Like Transcription Factors - genetics Life Sciences Male Mice Morphology Phenols - pharmacology Phenols - toxicity Pregnancy Receptor, IGF Type 2 - genetics Receptors, Estrogen - genetics Rodents
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