Association of midlife obesity and cardiovascular risk with old age frailty: a 26-year follow-up of initially healthy men

Objective and hypothesis: To investigate whether old age frailty is predicted by midlife overweight/obesity and cardiovascular disease (CVD) risk. Design: Longitudinal observational study (the Helsinki Businessmen Study). Subjects: In their midlife in 1974, 1815 initially healthy men (mean age 47 ye...

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Veröffentlicht in:	International Journal of Obesity 2012-09, Vol.36 (9), p.1153-1157
Hauptverfasser:	Strandberg, T E, Sirola, J, Pitkälä, K H, Tilvis, R S, Strandberg, A Y, Stenholm, S
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/2743/393 692/699/75 692/700/1518 Aged Aged, 80 and over Aging Biological and medical sciences Blood pressure Body Mass Index Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - epidemiology Cardiovascular Diseases - etiology Cardiovascular Diseases - mortality Cholesterol Complications and side effects Coronary vessels Disability Evaluation Disease Progression Epidemiology Exercise Finland - epidemiology Follow-Up Studies Frail elderly Frail Elderly - statistics & numerical data Frailty Geriatric Assessment geriatric-original-article Geriatrics Glucose Health aspects Health Behavior Health care Health Promotion and Disease Prevention Health risks Health sciences Hospitals Humans Internal Medicine Longitudinal Studies Male Medical sciences Medicine Medicine & Public Health Metabolic Diseases Middle age Middle Aged Miscellaneous Mortality Obesity Obesity - complications Obesity - epidemiology Obesity - mortality Observational studies Overweight Prevalence Public Health Public health. Hygiene Public health. Hygiene-occupational medicine Questionnaires Risk Factors Risk factors (Health) Risk management Surveys and Questionnaires Vein & artery diseases Weight control
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Beschreibung
Zusammenfassung:	Objective and hypothesis: To investigate whether old age frailty is predicted by midlife overweight/obesity and cardiovascular disease (CVD) risk. Design: Longitudinal observational study (the Helsinki Businessmen Study). Subjects: In their midlife in 1974, 1815 initially healthy men (mean age 47 years) were clinically investigated, whereupon their weight status (normal weight
ISSN:	0307-0565 1476-5497
DOI:	10.1038/ijo.2012.83