The Effect of Monomer Order on the Hydrolysis of Biodegradable Poly(lactic-co-glycolic acid) Repeating Sequence Copolymers

The effect of sequence on copolymer properties is rarely studied despite the precedent from Nature that monomer order can create materials of significant diversity. Poly(lactic-co-glycolic acid) (PLGA), one of the most important biodegradable copolymers, is widely used in an unsequenced, random form...

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Veröffentlicht in:	Journal of the American Chemical Society 2012-10, Vol.134 (39), p.16352-16359
Hauptverfasser:	Li, Jian, Rothstein, Sam N, Little, Steven R, Edenborn, Harry M, Meyer, Tara Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatible Materials - chemistry Capsules Drug Carriers - chemical synthesis Drug Carriers - chemistry Hydrolysis Lactic Acid - chemical synthesis Lactic Acid - chemistry Lactic Acid - metabolism Polyglycolic Acid - chemical synthesis Polyglycolic Acid - chemistry Rhodamines - chemistry Rhodamines - metabolism Temperature
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