Airway distensibility with lung inflation after allogeneic haematopoietic stem-cell transplantation

Highlights ► We hypothesized that airway distensibility is increased after allogeneic HSCT. ► Respiratory system conductance ( Grs ) was measured by FOT and lung density by CT. ► Grs showed a slight (ranging from 12 to 16%) but significant increase after HSCT. ► Airway distensibility with lung infla...

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Veröffentlicht in:	Respiratory physiology & neurobiology 2012-10, Vol.184 (1), p.80-85
Hauptverfasser:	Barisione, Giovanni, Pompilio, Pasquale P, Bacigalupo, Andrea, Brusasco, Claudia, Cioè, Alex, Dellacà, Raffaele L, Lamparelli, Teresa, Garlaschi, Alessandro, Pellegrino, Riccardo, Brusasco, Vito
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Airway distensibility with lung inflation Allogeneic haematopoietic stem-cell transplantation Bronchiolitis obliterans syndrome Female Forced oscillation technique Hematologic Neoplasms - therapy Hematopoietic Stem Cell Transplantation - adverse effects Humans Lung - physiopathology Lung Compliance Male Medical Education Pulmonary/Respiratory Respiratory Function Tests Respiratory system conductance Transplantation, Homologous
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Zusammenfassung:	Highlights ► We hypothesized that airway distensibility is increased after allogeneic HSCT. ► Respiratory system conductance ( Grs ) was measured by FOT and lung density by CT. ► Grs showed a slight (ranging from 12 to 16%) but significant increase after HSCT. ► Airway distensibility with lung inflation increased and was correlated with lung density.
ISSN:	1569-9048 1878-1519
DOI:	10.1016/j.resp.2012.07.021