Determining cut-off values for neck circumference as a measure of the metabolic syndrome amongst a South African cohort: the SABPA study

The aim was to determine receiver operating characteristic (ROC) neck circumference (NC) cut offs best associated with the metabolic syndrome (MetS) in a South African cohort. We included 409 urban Africans and Caucasians and stratified them into gender and age groups (25–45 years; 45–65 years). Mea...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Endocrine 2012-10, Vol.42 (2), p.335-342
Hauptverfasser: Hoebel, S., Malan, L., de Ridder, J. H.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The aim was to determine receiver operating characteristic (ROC) neck circumference (NC) cut offs best associated with the metabolic syndrome (MetS) in a South African cohort. We included 409 urban Africans and Caucasians and stratified them into gender and age groups (25–45 years; 45–65 years). Measurements included anthropometric, fasting overnight urine and biological markers for the MetS (systolic and diastolic blood pressure, glucose, triglycerides, and high density lipoprotein). ROC analysis determined pathological (NC) cut-points of 39 and 35 cm for young and older African men; 32 and 35 cm for young and old African women; 40 and 41 cm for Caucasian men; 34 and 33 cm for Caucasian women. Pathological NC cut-points significantly predicted MetS in all ethnic–gender–age groups except in African women (ORs 2.3–5.4; 95% CI 1.36–16.5). Multiple regression analyses revealed that MetS prevalence and ROC cut-points were not associated with renal impairment in any groups. ROC NC cut-points demonstrated that NC may be used as an additional anthropometric marker to predict the MetS in a South African cohort but not in African women.
ISSN:1355-008X
1559-0100
DOI:10.1007/s12020-012-9642-y