A fully liquid DTaP-IPV-Hep B-PRP-T hexavalent vaccine for primary and booster vaccination of healthy Mexican children

Highlights ► Consistency of 3 lots of Hexaxim was demonstrated. ► Good immunogenicity following Hexaxim 2, 4, 6 month primary series, similar to control. ► High degree of antibody persistence at 15–18 months of age. ► Strong immune response following Hexaxim booster. ► No safety concerns for primary...

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Veröffentlicht in:	Vaccine 2012-10, Vol.30 (45), p.6492-6500
Hauptverfasser:	Aquino, Amalia Guadalupe Becerra, Brito, Maricruz Gutiérrez, Doniz, Carlos E. Aranza, Herrera, Juan Francisco Galán, Macias, Mercedes, Zambrano, Betzana, Plennevaux, Eric, Santos-Lima, Eduardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Allergy and Immunology Aluminum Anorexia Antibodies, Bacterial - blood Antibodies, Viral - blood Antigens Booster vaccination Diphtheria-Tetanus-acellular Pertussis Vaccines - administration & dosage Diphtheria-Tetanus-acellular Pertussis Vaccines - adverse effects Diphtheria-Tetanus-acellular Pertussis Vaccines - immunology Haemophilus Vaccines - administration & dosage Haemophilus Vaccines - adverse effects Haemophilus Vaccines - immunology Hepatitis Hepatitis B Vaccines - administration & dosage Hepatitis B Vaccines - adverse effects Hepatitis B Vaccines - immunology Hexavalent vaccine Humans Immune response Immunization, Secondary Immunogenicity Infant Licenses Mexico Poliovirus Vaccine, Inactivated - administration & dosage Poliovirus Vaccine, Inactivated - adverse effects Poliovirus Vaccine, Inactivated - immunology Primary vaccination Tetanus Vaccines Vaccines, Combined - administration & dosage Vaccines, Combined - adverse effects Vaccines, Combined - immunology Whooping cough
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Beschreibung
Zusammenfassung:	Highlights ► Consistency of 3 lots of Hexaxim was demonstrated. ► Good immunogenicity following Hexaxim 2, 4, 6 month primary series, similar to control. ► High degree of antibody persistence at 15–18 months of age. ► Strong immune response following Hexaxim booster. ► No safety concerns for primary series or booster vaccinations.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2012.07.040