In vivo two-photon fluorescent imaging of fluoride with a desilylation-based reactive probe

A two-photon excitable molecular probe for fluoride, developed based on a fluoride-specific desilylation reaction, is demonstrated to be useful for fluorescent imaging of fluoride ions in live zebrafish by one-photon as well as two-photon microscopy for the first time.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2012-10, Vol.48 (82), p.10243-10245
Hauptverfasser:	Kim, Dokyoung, Singha, Subhankar, Wang, Taejun, Seo, Eunseok, Lee, Jun Ho, Lee, Sang-Joon, Kim, Ki Hean, Ahn, Kyo Han
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line, Tumor Fluorescence Fluorides - chemistry Mice Molecular Probes - chemistry Molecular Structure Organosilicon Compounds - chemistry Photons Zebrafish
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	A two-photon excitable molecular probe for fluoride, developed based on a fluoride-specific desilylation reaction, is demonstrated to be useful for fluorescent imaging of fluoride ions in live zebrafish by one-photon as well as two-photon microscopy for the first time.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c2cc35668f