Importance of the Candida albicans cell wall during commensalism and infection

Highlights ► The Candida cell wall contains virulence factors, antigens and PAMPs. ► The cell wall is cortical for the transition between commensalism and virulence. ► The yeast to hypha transition markedly affects wall composition and immune reactivity. ► Cellular morphogenesis is critical for the...

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Veröffentlicht in:	Current opinion in microbiology 2012-08, Vol.15 (4), p.406-412
Hauptverfasser:	Gow, Neil AR, Hube, Bernhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Candida albicans Candida albicans - immunology Candida albicans - pathogenicity Candida albicans - physiology Candidiasis - immunology Candidiasis - microbiology Cell surface Cell Wall - immunology Cell Wall - metabolism cell wall components Cell walls coevolution Commensalism Commensals Cytology defense mechanisms Fundamental and applied biological sciences. Psychology Fungal Proteins - metabolism genes Humans Immune system Infection Microbiology Miscellaneous Mucosa Mycology pathogenesis Pathogens Pathology Reviews Symbiosis Virulence Factors yeasts
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Beschreibung
Zusammenfassung:	Highlights ► The Candida cell wall contains virulence factors, antigens and PAMPs. ► The cell wall is cortical for the transition between commensalism and virulence. ► The yeast to hypha transition markedly affects wall composition and immune reactivity. ► Cellular morphogenesis is critical for the equilibrium between commensalism and virulence.
ISSN:	1369-5274 1879-0364
DOI:	10.1016/j.mib.2012.04.005