Relief of intractable posthypoxic myoclonus after administration of agomelatine

Chronic posthypoxic myoclonus is characterized by myoclonic jerks that are specifically triggered by action. It is a rare but devastating sequela of hypoxic encephalopathy. We report a 42-year-old female patient with treatment-resistant chronic posthypoxic myoclonus, which improved with administrati...

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Veröffentlicht in:	Clinical neuropharmacology 2012-09, Vol.35 (5), p.258-259
Hauptverfasser:	González de la Aleja, Jesús, Saiz-Díaz, Rosa Ana, De la Peña, Pilar
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetamides - pharmacology Acetamides - therapeutic use Adult Female Humans Hypoxia, Brain - complications Hypoxia, Brain - diagnosis Hypoxia, Brain - drug therapy Melatonin - agonists Myoclonus - diagnosis Myoclonus - drug therapy Myoclonus - etiology
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Zusammenfassung:	Chronic posthypoxic myoclonus is characterized by myoclonic jerks that are specifically triggered by action. It is a rare but devastating sequela of hypoxic encephalopathy. We report a 42-year-old female patient with treatment-resistant chronic posthypoxic myoclonus, which improved with administration of the drug agomelatine. We suggest that agomelatine could represent a useful therapeutic option in the treatment of chronic posthypoxic myoclonus.
ISSN:	0362-5664 1537-162X
DOI:	10.1097/WNF.0b013e3182613e06