Axillary recurrences after sentinel lymph node biopsy: A multicentre analysis and follow-up of sentinel lymph node negative breast cancer patients

Abstract Introduction The objective of this study was to conduct a multicentre data analysis to identify prognostic factors for developing an axillary recurrence (AR) after negative sentinel lymph node biopsy (SLNB) in a large cohort of breast cancer patients with long follow-up. Patients and method...

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Veröffentlicht in:	European journal of surgical oncology 2012-10, Vol.38 (10), p.925-931
Hauptverfasser:	van Wely, B.J, van den Wildenberg, F.J.H, Gobardhan, P, van Dalen, T, Borel Rinkes, I.H.M, Theunissen, E.B.M, Wijsman, J.H, Ernst, M, van der Pol, C.C, Madsen, E.V.E, Vles, W.J, Wauters, C.A.P, de Wilt, J.H.W, Strobbe, L.J.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Axilla Axillary recurrences Breast cancer Breast Neoplasms - mortality Breast Neoplasms - pathology Breast Neoplasms - therapy Cohort Studies Combined Modality Therapy Confidence Intervals Databases, Factual Disease-Free Survival Female Follow-Up Studies Hematology, Oncology and Palliative Medicine Humans Lymph Node Excision - methods Lymph Nodes - pathology Middle Aged Multivariate Analysis Neoplasm Recurrence, Local - etiology Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - pathology Neoplasm Staging Odds Ratio Prognostic factors Prospective Studies Radiation therapy Risk Assessment Sentinel Lymph Node Biopsy - adverse effects Sentinel Lymph Node Biopsy - methods Sentinel Lymph Node Biopsy - statistics & numerical data Surgery Survival Analysis Treatment Outcome
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Zusammenfassung:	Abstract Introduction The objective of this study was to conduct a multicentre data analysis to identify prognostic factors for developing an axillary recurrence (AR) after negative sentinel lymph node biopsy (SLNB) in a large cohort of breast cancer patients with long follow-up. Patients and methods The prospective databases from different hospitals of clinically node negative breast cancer patients operated on between, 2000 and 2002 were analyzed. SLNB was performed and pathological analysis done by local pathologists according to national guidelines. Adjuvant treatment was given according to contemporary guidelines. Multivariate analysis was performed using all available variables, a p -value of
ISSN:	0748-7983 1532-2157
DOI:	10.1016/j.ejso.2012.04.016