Inflammatory and thrombotic changes in early bereavement: a prospective evaluation

Aims: Although there is an increased cardiovascular risk in the immediate weeks following bereavement, the mechanism is not well understood. The aim of this study was to determine whether inflammatory and thrombotic changes were present in acute bereavement. Methods and results: Eighty bereaved spou...

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Veröffentlicht in:	European journal of preventive cardiology 2012-10, Vol.19 (5), p.1145-1152
Hauptverfasser:	Buckley, Thomas, Morel-Kopp, Marie-Christine, Ward, Christopher, Bartrop, Roger, McKinley, Sharon, Mihailidou, Anastasia Susie, Spinaze, Monica, Chen, Walter, Tofler, Geoffrey
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Bereavement Female Follow-Up Studies Hemostasis - physiology Humans Incidence Inflammation - blood Inflammation - epidemiology Inflammation - psychology Male Middle Aged New South Wales - epidemiology Parents - psychology Prospective Studies Risk Assessment Risk Factors Spouses - psychology Thrombosis - blood Thrombosis - epidemiology Thrombosis - psychology
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Zusammenfassung:	Aims: Although there is an increased cardiovascular risk in the immediate weeks following bereavement, the mechanism is not well understood. The aim of this study was to determine whether inflammatory and thrombotic changes were present in acute bereavement. Methods and results: Eighty bereaved spouses or parents were prospectively studied within 2 weeks of bereavement (acute) and at 6 months, and compared to 80 non-bereaved participants. Haemostatic measures were obtained between 8 a.m. and 11 a.m. and processed within 1 h. Compared to non-bereaved participants, those acutely bereaved had a higher neutrophil count (4.34 ± 0.19 vs 3.79 ± 0.15, p =
ISSN:	2047-4873 2047-4881
DOI:	10.1177/1741826711421686